PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.
Anti-PAR Monoclonal Antibody w/Control
R&D Systems | Catalog # 4335-MC-100-AC
Discontinued Product
4335-MC-100-AC has been discontinued.
View all PAR/pADPr products.
Key Product Details
Species Reactivity
Validated:
Multi-Species
Cited:
Human, Mouse
Applications
Western Blot, Flow Cytometry, Immunoprecipitation
Label
Unconjugated
Antibody Source
Monoclonal Clone # 10HA
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Product Specifications
Clonality
Monoclonal
Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: PAR/pADPr
Long Name
Poly [ADP-ribose] Polymer
Alternate Names
PAR
Additional PAR/pADPr Products
Product Documents for Anti-PAR Monoclonal Antibody w/Control
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Anti-PAR Monoclonal Antibody w/Control
For research use only
Related Research Areas
Citations for Anti-PAR Monoclonal Antibody w/Control
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