Atiprimod dihydrochloride

   
Product Datasheet
Catalog Number:4580
Chemical Name:N,N-Diethyl-8,8-dipropyl-2-azaspiro[4.5]decane-2-propanamine dihydrochloride
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Biological Activity
JAK2 inhibitor (IC50 = 397 nM). Also inhibits STAT3 and STAT5 phosphorylation. Inhibits cell growth and induces apoptosis in cells expressing the JAK2V617F mutation.
Technical Data
  • M.Wt:
    409.52
  • Formula:
    C22H44N2.2HCl
  • Solubility:
    Soluble to 50 mM in water and to 10 mM in DMSO with gentle warming
  • Storage:
    Desiccate at RT
  • CAS No:
    130065-61-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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