Azithromycin

  ( 1 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:3771
Alternate Names:CP 62993
Chemical Name:13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
Product Details
Citations (1)
Reviews
Biological Activity
Macrolide antibiotic. Inhibits 50S ribosomal subunit formation and elongation at transpeptidation step in gram-positive and gram-negative organisms. Orally active with improved pharmacokinetics over erythromycin in mouse models. Inhibits autophagy.
Technical Data
  • M.Wt:
    748.98
  • Formula:
    C38H72N2O12
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at -20°C
  • CAS No:
    83905-01-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.
Product Datasheets
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Azithromycin include:

1 Citations: Showing 1 - 1

  1. The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin.
    Authors: Broad and Sanger
    Br J Pharmacol  2013;168:1859

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Average Rating: 5 (Based on 1 review)

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  Excellent
  Human John Broad 01/05/2018
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Summary

Species Human

Other Experimental Details

Other Experimental Details Use at 100-300uM for efficacy as motilin agonist

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Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

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