Macrolide antibiotic. Inhibits 50S ribosomal subunit formation and elongation at transpeptidation step in gram-positive and gram-negative organisms. Orally active with improved pharmacokinetics over erythromycin in mouse models.
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Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms.
Retsema et al.
Antimicrob.Agents Chemother., 1987;31:1939
Macrolide antibiotics inhibit 50S ribosomal subunit assembly in Bacillus subtilis and Staphylococcus aureas.
Champney and Burdine
Antimicrob.Agents Chemother., 1995;39:2141
Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new macrolide with extended half-life and excellent tissue distribution.
Girard et al.
Antimicrob.Agents Chemother., 1987;31:1948
The citations listed below are publications that use Tocris products. Selected citations for Azithromycin include:
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