Home / Additional Bcl-2 Family Compounds / BAM 7

BAM 7

4810 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4810/10
4810/50
BAM 7 | CAS No. 331244-89-4 | Additional Bcl-2 Family Compounds
1 Image
Description: Selective Bax activator; induces Bax-mediated apoptosis

Chemical Name: 3-Methyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone]

Purity: ≥99%

Product Details
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

BAM 7 is a Bax activator (EC50 = 3.3 μM); binds at the BH3-binding site. Selective for Bax over other antiapoptotic and proapoptotic proteins. Triggers Bax oligomerization in vitro; induces Bax-mediated apoptosis in mouse embryonic fibroblasts.

Technical Data

M.Wt:
405.47
Formula:
C21H19N5O2S
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
331244-89-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Direct and selective small-molecule activation of proapoptotic BAX.
    Gavathiotis et al.
    Nat.Chem.Biol., 2012;8:639

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for BAM 7

There are currently no reviews for this product. Be the first to review BAM 7 and earn rewards!

Have you used BAM 7?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.