BIO-acetoxime

  ( 1 citations )    
Product Datasheet
Catalog Number:3874
Chemical Name:(2'Z,3'E)-6-Bromoindirubin-3'-acetoxime
Product Details
Citations (1)
Reviews
Biological Activity
Selective GSK-3α/β inhibitor (IC50 values are 0.01, 2.4, 4.3 and 63 μM for GSK-3α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling and inhibits CD8+ T cell effector differentiation.
Technical Data
  • M.Wt:
    398.21
  • Formula:
    C18H12BrN3O3
  • Solubility:
    Soluble to 20 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    667463-85-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for BIO-acetoxime include:

1 Citations: Showing 1 - 1

  1. GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation.
    Authors: Penas Et al.
    Sci Rep  2015;14:417

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