BPDE Antibody

R&D Systems | Catalog # 4360-MC-100

R&D Systems
Discontinued Product
4360-MC-100 has been discontinued. View all BPDE products.

Key Product Details

Species Reactivity

Multi-Species

Applications

Validated:

Competitive ELISA

Cited:

Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 8E11
View all BPDE Primary Antibodies »

Product Specifications

Immunogen

BPDE-I-G coupled to BSA

Specificity

The antibody recognizes both free polycyclic aromatic hydrocarbons (PAHs) and DNA adducts.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for BPDE Antibody

Application
Recommended Usage

Competitive ELISA

In an inhibition assay, the binding of the antibody to BPDE adducts was inhibited by BPDE-I-DNA, BPDE-I-dG, BPDE-I tetraol but not by BPDE-II-DNA.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from ascites

Formulation

This antibody is provided from mouse ascites, provided at 1 mg/ml in PBS, 50% glycerol.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Stored at -20 °C. For long term storage, freeze in working aliquots at -20 °C in a manual defrost freezer to avoid repeated freeze-thawings.

Background: BPDE

The antibody may be used to investigate exposure to environmental and occupational pollutants. PAHs are released into the environment following incomplete combustion of organic materials. Human exposure to PAHs comes from various occupational, environmental, dietary and medicinal sources. Exposure to this group of compounds is believed to be carcinogenic.

Long Name

Benzo[A] Pyrene-Diol Epoxide

Alternate Names

Benzo Pyrene Dihydrodiol Epoxide

Additional BPDE Products

Product Documents for BPDE Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for BPDE Antibody

For research use only

Related Research Areas

DNA Repair

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