HDAC5 and HDAC9 inhibitor (IC50
values are 0.85 and 1.88 μ
M, respectively). Also weakly inhibits HDAC4, HDAC6, HDAC7 and HDAC8 (IC50
values are 3.88 - 13.8 μ
M). Exhibits >20-fold selectivity for HDAC5/9 over HDAC1/2/3.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Inhibition of zinc-dependent histone deacetylases with a chemically triggered electrophile.
Boskovic et al.
ACS Chem.Biol., 2016;11:1844