Catalog Number: 6010
Chemical Name: 5-Chloro-7-[(4-ethyl-1-piperazinyl)-3-pyridinylmethyl]-8-quinolinol
Biological Activity
HDAC5 and HDAC9 inhibitor (IC50 values are 0.85 and 1.88 μM, respectively). Also weakly inhibits HDAC4, HDAC6, HDAC7 and HDAC8 (IC50 values are 3.88 - 13.8 μM). Exhibits >20-fold selectivity for HDAC5/9 over HDAC1/2/3.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 20 mM in DMSO and to 50 mM in ethanol
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibition of zinc-dependent histone deacetylases with a chemically triggered electrophile.
    Boskovic et al.
    ACS Chem.Biol., 2016;11:1844
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