BRD 9757
Chemical Name: N-Hydroxy-1-cyclopentene-1-carboxamide
Purity: ≥98%
Biological Activity
BRD 9757 is a potent and selective HDAC6 inhibitor (IC50 = 30 nM). Displays selectivity for HDAC6 over Class I HDACS (>20-fold) and Class II HDACs (>400-fold).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Potent and selective inhibition of histone deacetylase 6 (HDAC6) does not require a surface-binding motif.
Wagner et al.
J.Med.Chem., 2013;56:1772
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