Catalog Number: 2808
Chemical Name: [5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol hydrochloride
Biological Activity
ORL1 receptor agonist that also displays mixed antagonist/partial agonist activity at κ, δ and μ-opioid receptors.
Technical Data
  • M.Wt:
    504.1
  • Formula:
    C29H41NO4.HCl
  • Solubility:
    Soluble to 25 mM in water and to 50 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    53152-21-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Agonist effect of buprenorphine in a nociceptin/OFQ receptor-triggered reporter gene assay.
    Wnendt et al.
    Mol.Pharmacol., 1999;56:334
  2. Behavioral pharmacology of buprenorphine, with a focus on preclinical models of reward and addiction.
    Tzschentke
    Psychopharmacology, 2002;161:1

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