BW 373U86

Key Product Details

Product Description

BW 373U86 is a potent, selective non-peptide δ-opioid receptor agonist. K_i values are 1.8, 15 and 34 nM for δ, μ and κ receptors respectively. Centrally active following systemic administration in vivo.

Licensing Information

Sold for research purposes under agreement from GlaxoSmithKline

Product Specifications for BW 373U86

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for BW 373U86

The following data is based on the product molecular weight 435.61.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.30 mL	11.48 mL	22.96 mL
5 mM	0.46 mL	2.30 mL	4.59 mL
10 mM	0.23 mL	1.15 mL	2.30 mL
50 mM	0.05 mL	0.23 mL	0.46 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 11 publications citing the usage of this product.

• Chang A novel, potent and selective nonpeptidic delta opioid receptor agonist BW373U86. J.Pharmacol.Exp.Ther. 1993 PMID: 8246159
• Dykstra A novel delta opioid agonist, BW373U86, in squirrel monkeys responding under a schedule of shock titration. J.Pharmacol.Exp.Ther. 1993 PMID: 8246162
• Broom Comparison of receptor mechanisms and efficacy requirements for δ-agonist-induced convulsive activity and antinociception in mice. J.Pharmacol.Exp.Ther. 2002 PMID: 12388657

Product Documents for BW 373U86