Chemical Name: 4-[(αR*)-α-((2S*,5R*)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl]-N,N-diethylbenzamide
Biological ActivityPotent, selective non-peptide δ-opioid receptor agonist. Ki values are 1.8, 15 and 34 nM for δ, μ and κ receptors respectively. Centrally active following systemic administration in vivo.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Comparison of receptor mechanisms and efficacy requirements for δ-agonist-induced convulsive activity and antinociception in mice.
Broom et al.
A novel, potent and selective nonpeptidic delta opioid receptor agonist BW373U86.
Chang et al.
A novel delta opioid agonist, BW373U86, in squirrel monkeys responding under a schedule of shock titration.
Dykstra et al.
Citation for BW 373U86
The citations listed below are publications that use Tocris products. Selected citations for BW 373U86 include:
1 Citation: Showing 1 - 1
Obesity improves myocardial ischaemic tolerance and RISK signalling in Ins-insensitive rats.
Authors: Donner Et al.
J Allergy Clin Immunol 2013;6:457
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