Catalog Number: 1663
Chemical Name: 4-[(αR*)-α-((2S*,5R*)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl]-N,N-diethylbenzamide
Biological Activity
Potent, selective non-peptide δ-opioid receptor agonist. Ki values are 1.8, 15 and 34 nM for δ, μ and κ receptors respectively. Centrally active following systemic administration in vivo.
Technical Data
  • M.Wt:
    435.61
  • Formula:
    C27H37N3O2
  • Solubility:
    Soluble to 100 mM in 1eq. HCl
  • Purity:
    >99%
  • Storage:
    Store at +4°C
  • CAS No:
    155836-50-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline
Background References
  1. Comparison of receptor mechanisms and efficacy requirements for δ-agonist-induced convulsive activity and antinociception in mice.
    Broom et al.
    J.Pharmacol.Exp.Ther., 2002;303:723
  2. A novel, potent and selective nonpeptidic delta opioid receptor agonist BW373U86.
    Chang et al.
    J.Pharmacol.Exp.Ther., 1993;267:852
  3. A novel delta opioid agonist, BW373U86, in squirrel monkeys responding under a schedule of shock titration.
    Dykstra et al.
    J.Pharmacol.Exp.Ther., 1993;267:875
Citations:

The citations listed below are publications that use Tocris products. Selected citations for BW 373U86 include:

1 Citations: Showing 1 - 1

  1. Obesity improves myocardial ischaemic tolerance and RISK signalling in insulin-insensitive rats.
    Authors: Donner Et al.
    J Allergy Clin Immunol 2013;6:457

Have you used BW 373U86?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information