BW 723C86 hydrochloride

Catalog # Availability Size / Price Qty
1059/10
1059/50
Cat.No. 1059 - BW 723C86 hydrochloride | C16H18N2OS.HCl | CAS No. 160521-72-2
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Description: 5-HT2B agonist

Chemical Name: α-methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine hydrochloride

Purity: ≥99%

Product Details
Citations (10)
Supplemental Products
Reviews

Biological Activity

Selective 5-HT2B receptor agonist.

Technical Data

M.Wt:
322.85
Formula:
C16H18N2OS.HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
160521-72-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for BW 723C86 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for BW 723C86 hydrochloride include:

10 Citations: Showing 1 - 10

  1. Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells.
    Authors: Szabo
    Sci Rep  2018;8(1):1765
  2. σ1 receptor ligands control a switch between passive and active threat responses.
    Authors: Rennekamp Et al.
    Nat Chem Biol  2016;12:552
  3. 5-HT is a potent relaxant in rat superior mesenteric veins.
    Authors: Watts Et al.
    PLoS One  2015;3:e00103
  4. Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude.
    Authors: Gerhold Et al.
    J Neurosci  2015;35:9580
  5. Mammary gland serotonin regulates parathyroid hormone-related protein and other bone-related signals.
    Authors: Hernandez Et al.
    Pharmacol Res Perspect  2012;302:E1009
  6. Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network.
    Authors: Niebert Et al.
    J Pharmacol Exp Ther  2011;6:e21395
  7. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
    Authors: Murray Et al.
    J Neurophysiol  2011;106:925
  8. Lack of serotonin 5-HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo.
    Authors: Tharayil Et al.
    Neurogastroenterol Motil  2010;22:462
  9. Protein kinase C{gamma} mediates regulation of proliferation by the serotonin 5-hydroxytryptamine receptor 2B.
    Authors: Wouters Et al.
    J Biol Chem  2009;284:21177
  10. Investigation of the role of 5-HT2 receptor subtypes in the control of the bladder and the urethra in the anaesthetized female rat.
    Authors: Mbaki
    Br J Pharmacol  2008;155:343

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