Product Datasheet
Catalog Number:0543
Alternate Names:HA 100
Chemical Name:1-(5-Isoquinolinesulfonyl)piperazine
Product Details
Biological Activity
Protein kinase inhibitor. Inhibits PKG, PKA and PKC (IC50 values are 4, 8 and 12 �M, respectively). Widely used as a ROCK inhibitor. Increases efficiency of human fibroblast reprogramming with PD 0325901 (Cat.No 4192), CHIR 99021 (Cat.No 4432), A 83-01 (Cat.No 2939) and hLIF. Improves survival of human pluripotent stem cells in culture.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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