Aldehyde oxidase (AO) substrate. Exhibits activities as a phosphodiesterase inhibitor; produces concentration-dependent positive inotropic responses in isolated right atria.
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Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes.
Hutzler et al.
Drug Metab.Dispos., 2011;40:267
Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition.
Shahid and Rodger et al.