CD21 Antibody (GB25A)

Novus Biologicals | Catalog # NBP2-60855

Novus Biologicals
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Key Product Details

Species Reactivity

Bison, Bovine, Goat, Sheep, Water Buffalo

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # GB25A
View all CD21 Primary Antibodies »

Product Specifications

Immunogen

Goat ConA stimulated mononuclear leukocytes

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

This monoclonal antibody is made in ascites form using mice. The ascites is collected and centrifuged to remove cells and large particles. The ascitic fluid is purified further by filtration through sequential filters with the last filter at 2 um. The concentration of the monoclonal antibody present in the ascites is determined with commercial radial immunodiffusion kits (1mg/ml).

Scientific Data Images for CD21 Antibody (GB25A)

Flow Cytometry: CD21 Antibody (GB25A) [NBP2-60855]

Flow Cytometry: CD21 Antibody (GB25A) [NBP2-60855]

Flow Cytometry: CD21 Antibody (GB25A) [NBP2-60855] - Obtained with bovine leukocytes

Applications for CD21 Antibody (GB25A)

Application
Recommended Usage

Flow Cytometry

1:10 - 1:1000

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Flow Cytometry

Formulation, Preparation, and Storage

Formulation

Ascites

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD21

CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.

Alternate Names

C3DR, CD21, CR2

Gene Symbol

CR2

Additional CD21 Products

Product Documents for CD21 Antibody (GB25A)

Certificate of Analysis

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Product Specific Notices for CD21 Antibody (GB25A)

This monoclonal antibody is made in ascites form using mice. The ascites is collected and centrifuged to remove cells and large particles. The ascitic fluid is purified further by filtration through sequential filters with the last filter at 2 um. The concentration of the monoclonal antibody present in the ascites is determined with commercial radial immunodiffusion kits (1mg/ml).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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