CD45RC Antibody (MIL15) - BSA Free

Novus Biologicals | Catalog # NB100-65001

Novus Biologicals
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Key Product Details

Species Reactivity

Porcine

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgM Clone # MIL15

Format

BSA Free
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Product Specifications

Immunogen

Cells isolated from porcine mesenteric lymph node

Specificity

Recognizes a restricted CD45 epitope encoded by the CD45 C exon.

Clonality

Monoclonal

Host

Mouse

Isotype

IgM

Scientific Data Images for CD45RC Antibody (MIL15) - BSA Free

Flow Cytometry: CD45RC Antibody (MIL15) [NB100-65001]

Flow Cytometry: CD45RC Antibody (MIL15) [NB100-65001]

Flow Cytometry: CD45RC Antibody (MIL15) [NB100-65001] - Figure A. Purified mouse anti porcine CD45RC detected with goat anti mouse IgM PE and mouse IgG1 FITC isotype control. Figure B. Purified mouse anti porcine CD45RC detected with goat anti mouse IgM PE and mouse anti porcine CD3 FITC. All experiments performed on red cell lysed porcine blood gated on mononuclear cells.
Flow Cytometry: CD45RC Antibody (MIL15) [NB100-65001]

Flow Cytometry: CD45RC Antibody (MIL15) [NB100-65001]

Flow Cytometry: CD45RC Antibody (MIL15) [NB100-65001] - Figure A. FITC conjugated mouse anti porcine CD3 and purified mouse IgM isotype control detected with goat anti mouse IgM PE. Figure B. FITC conjugated mouse anti porcine CD3 and purified mouse anti porcine CD45RC detected with goat anti mouse IgM. All experiments performed on red cell lysed porcine blood gated on mononuclear cells.

Applications for CD45RC Antibody (MIL15) - BSA Free

Application
Recommended Usage

Flow Cytometry

Neat

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

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Formulation, Preparation, and Storage

Purification

Tissue culture supernatant

Formulation

Tissue culture supernatant

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD45RC

CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognizing a common epitope on all of the isoforms are termed CD45 whilst those recognizing only individual isoforms are termed CD45RA or CD45RO etc.

Alternate Names

B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Gene Symbol

PTPRC

Additional CD45RC Products

Product Documents for CD45RC Antibody (MIL15) - BSA Free

Certificate of Analysis

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Product Specific Notices for CD45RC Antibody (MIL15) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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