Chemical Name: N-Acetylsphingosine
Biological ActivityA potent modulator of cell proliferation and differentiation. Activates protein phosphatase-1 (PP1) and -2A (PP2A), as well as ceramide-activated protein phosphatase (CAPP) in vitro.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Ceramide stimulates a cytosolic protein phosphatase.
Dobowsky and Hannun
Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor α and γ-IF..
Kim et al.
Ceramide mediates the apoptotic response of WEHI 231 cells to anti-immunoglobulin, corticosteroids and irradiation.
Quintans et al.
Ceramide selectively decreases tau levels in differentiated PC12 cells through modulation of calpain I.
Xie and Johnson
Citation for Ceramide
The citations listed below are publications that use Tocris products. Selected citations for Ceramide include:
1 Citation: Showing 1 - 1
PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells.
Authors: Samokhvalov Et al.
Pharmacol Biochem Behav 2015;232:44105
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