Ceramide

Key Product Details

Product Description

Ceramide is a potent modulator of cell proliferation and differentiation. Activates protein phosphatase-1 (PP1) and -2A (PP2A), as well as ceramide-activated protein phosphatase (CAPP) in vitro.

Product Specifications for Ceramide

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Ceramide

The following data is based on the product molecular weight 341.53.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

5 4 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.93 mL	14.64 mL	29.28 mL
5 mM	0.59 mL	2.93 mL	5.86 mL
10 mM	0.29 mL	1.46 mL	2.93 mL
50 mM	0.06 mL	0.29 mL	0.59 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 31 publications citing the usage of this product.

• Xie and Johnson Ceramide selectively decreases tau levels in differentiated PC12 cells through modulation of calpain I. J.Neurochem. 1997 PMID: 9282924
• Kim Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor α and γ-IF.. J.Biol.Chem. 1991 PMID: 1845977
• Quintans Ceramide mediates the apoptotic response of WEHI 231 cells to anti-immunoglobulin, corticosteroids and irradiation. Biochem.Biophys.Res.Commun. 1994 PMID: 8048941
• Dobowsky and Hannun Ceramide stimulates a cytosolic protein phosphatase. J.Biol.Chem. 1992 PMID: 1312082

Product Documents for Ceramide