cGMP Dependent Kinase Inhibitor Peptide

Tocris Bioscience | Catalog # 1883

Inhibitor of protein kinases G and A
Tocris Bioscience
Discontinued Product
1883 has been discontinued. View all Protein Kinase A Inhibitors products.

Key Product Details

Description

Inhibitor of protein kinases G and A

Alternative Names

[Ala32]H2B(29-35)
View all Protein Kinase A Inhibitors »

Product Description

cGMP Dependent Kinase Inhibitor Peptide is a competitive inhibitor of cGMP-dependent protein kinase (PKG); analog of a substrate peptide corresponding to a phosphorylation site of histone H2B. Competes with synthetic substrates (Ki = 86 mM) but does not inhibit phosphorylation of intact histones by PKG. Inhibits phosphorylation of intact histones by PKA.

Product Specifications for cGMP Dependent Kinase Inhibitor Peptide

Molecular Weight

943.12

Formula

C38H74N18O10

Storage

Desiccate at -20°C

CAS Number

82801-73-8

PubChem ID

134097

InChI Key

OUKSKNTVYYVIMZ-DUJSLOSMSA-N

SMILES

[H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Product Documents for cGMP Dependent Kinase Inhibitor Peptide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for cGMP Dependent Kinase Inhibitor Peptide

For research use only

Customer Reviews for cGMP Dependent Kinase Inhibitor Peptide (1)

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  • We examined the regulatory mechanism of the PKG holoenzymes
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 02/26/2019
    We examined the regulatory mechanism of the PKG holoenzymes. The development of cGMP-independent peptide activators of PKG I alpha, derived from this helical segment was found bridging the regulatory and catalytic domains.
    cGMP Dependent Kinase Inhibitor Peptide 1883

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