Calmodulin antagonist; inhibits calmodulin-stimulated cAMP phosphodiesterase activity with an IC50
of 3.3 nM. Also prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+
currents in PC12 cells and inhibits nAChR.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
CGS 9343B, a novel, potent, and selective inhibitor of Calmodulin activity.
Norman et al.
Inhibition of membrane currents and rises of intracellular Ca2+ in PC12 cells by CGS 9343B, a calmodulin inhibitor.
Neuhaus and Reber
Calmodulin regulates the transcriptional activity of estrogen receptors.
Li et al.
The citations listed below are publications that use Tocris products. Selected citations for CGS 9343B include:
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