CGS 9343B

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2255/10
CGS 9343B | CAS No. 109826-27-9 | Calcium Binding Protein Modulator Antagonists
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Description: Calmodulin antagonist
Alternative Names: Zaldaride maleate

Chemical Name: 1,3-Dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]-4-piperidinyl]-2H-benzimidazol-2-one maleate

Purity: ≥98%

Product Details
Citations (2)
Reviews

Biological Activity

Calmodulin antagonist; inhibits calmodulin-stimulated cAMP phosphodiesterase activity with an IC50 of 3.3 nM. Also prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR.

Technical Data

M.Wt:
544.61
Formula:
C26H28N4O2.C4H4O4
Solubility:
Soluble to 50 mM in DMSO and to 10 mM in ethanol with gentle warming
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
109826-27-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for CGS 9343B

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