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Ciglitazone

Catalog #: 1307
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1307/10
1307/50
Ciglitazone | CAS No. 74772-77-3 | PPAR gamma Receptor Agonists
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Description: Selective PPARγ agonist

Chemical Name: 5-[[4-[(1-Methylcyclohexyl)methoxy]phenyl]methyl]-2,4-thiazolidinedione

Purity: ≥99%

Product Details
Citations (2)
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Biological Activity

Ciglitazone is a selective agonist at PPARγ (peroxisome proliferator-activated receptor γ). Activates PPARγ with an EC50 value of 3 μM in vitro, and is at least 33-fold selective over PPARα and δ. Antihyperglycemic in vivo.

Technical Data

M.Wt:
333.44
Formula:
C18H23NO3S
Solubility:
Soluble to 100 mM in 1eq. NaOH
Purity:
≥99%
Storage:
Store at RT
CAS No:
74772-77-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Reconstitution Calculator

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Citations for Ciglitazone

The citations listed below are publications that use Tocris products. Selected citations for Ciglitazone include:

2 Citations: Showing 1 - 2

  1. Pharmaceutical induction of ApoE secretion by multipotent mesenchymal stromal cells (MSCs).
    Authors: Zeitouni Et al.
    BMC Biotechnol  2008;8:75
  2. Regulation of cellular processes by PPARgamma ligands in neuroblastoma cells is modulated by the level of retinoblastoma protein expression.
    Authors: Emmans Et al.
    Biochem Soc Trans  2004;32:840

FAQs

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VersaClone cDNA Plasmids

Human PPAR gamma/NR1C3 (NP_056953) VersaClone cDNA

RDC1997

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