Topoisomerase I inhibitor. Forms stable DNA-topoisomerase complexes during DNA replication and induces cell cycle arrest in the G2
/M phase. Inhibits growth of a range of cancer cell lines in vitro
, as well as of ovarian and leukemia tumors in vivo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Anticancer effects of CKD-602 (Camtobell®) via G2/M phase arrest in oral squamous cell carcinoma cell lines.
Kim et al.
The synergism between Belotecan and cisplatin in gastric cancer.
Jung et al.
Cancer Res.Treat., 2006;38:159