Clofibrate

Catalog # Availability Size / Price Qty
0824/1G
Clofibrate | CAS No. 637-07-0 | Non-selective PPAR Receptor Agonists
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Description: PPAR agonist

Chemical Name: Ethyl 2-(4-chlorophenoxy)-2-methylpropionate

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Biological Activity

Clofibrate is a PPAR agonist (EC50 values are 50, 500 and > 100 μM at PPARα, PPARγ and PPARδ respectively). Antihyperlipoproteinemic.

Technical Data

M.Wt:
242.702
Formula:
C12H15ClO3
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store at RT
CAS No:
637-07-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. The PPARs: from orphan receptors to drug discovery.
    Willson et al.
    J.Med.Chem., 2000;43:527
  2. Peroxisome proliferator-activated receptors in the cardiovascular system.
    Bishop-Bailey
    Br.J.Pharmacol., 2000;129:823
  3. Mechanism of action of fibrates.
    Shepherd
    Postgrad.Med.J., 1993;69:S34

Product Datasheets

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Reconstitution Calculator

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⚠ WARNING: This product can expose you to chemicals including Clofibrate, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

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