(±)-Cloprostenol sodium salt

Key Product Details

Product Description

(±)-Cloprostenol sodium salt is a water-soluble prostaglandin F_2α (PGF_2α) analog; acts as a potent FP receptor agonist (EC₅₀ = 0.84 nM). Potently inhibits differentiation of adipocyte precursor cells. Luteolytic agent in vivo.

Product Specifications for (±)-Cloprostenol sodium salt

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for (±)-Cloprostenol sodium salt

The following data is based on the product molecular weight 446.90.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	11.19 mL	55.94 mL	111.88 mL
1 mM	2.24 mL	11.19 mL	22.38 mL
2 mM	1.12 mL	5.59 mL	11.19 mL
10 mM	0.22 mL	1.12 mL	2.24 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Griffin Pharmacological characterization of an FP prostaglandin receptor on rat vascular smooth muscle cells (A7r5) coupled to phosphoinositide turnover and intracellular calcium mobilization. J.Pharmacol.Exp.Ther. 1998 PMID: 9655886
• Serrero and Lepak Prostaglandin F_2α receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium. Biochem.Biophys.Res.Comm.
• Dukes Potent luteolytic agents related to prostaglandin F_2α. Nature 1974 PMID: 4853720

Product Documents for (±)-Cloprostenol sodium salt