7 results for "Prostanoid Receptor Agonists" in Products
Prostanoid Receptor Agonists
Prostanoid receptors are activated by the endogenous ligands prostaglandin (PG) D2, PGE2, PGF2α, PGH2, prostacyclin (PGI2) and thromboxane A2. Cyclooxygenase (COX) converts arachidonic acid to PGH2, from which the other prostaglandins are synthesized. Prostanoid receptors are a family of nine G-protein-coupled receptors that have distinct tissue distributions and actions.
- DP receptors (DP1-2) are coupled to Gαs. They are expressed in the small intestine, lung, stomach and uterus. ...
Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin
| Alternate Names: | PGE2 |
| Chemical Name: | (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid |
| Purity: | ≥98% |
Potent, stable thromboxane A2 (TP) receptor agonist
| Alternate Names: | 9,11-Dideoxy-9a,11a-methanoepoxy prostaglandin F2a |
| Chemical Name: | (5Z)-7-[(1R,4S,5S,6R)-6-[(1E,3S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]hept-5-yl]-5-heptenoic acid |
| Purity: | ≥98% |
Endogenous IP receptor agonist
| Alternate Names: | Prostaglandin I2,Prostacyclin |
| Chemical Name: | (5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt |
| Purity: | ≥98% |
Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development
| Chemical Name: | (5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxo-prosta-5,13-dien-1oic acid |
| Purity: | ≥95% |
Selective EP4 agonist
| Chemical Name: | (5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone |
| Purity: | ≥98% |
Naturally-occurring prostanoid; potent vasoconstrictor
| Chemical Name: | 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid tris(hydroxymethyl)aminomethane salt |
| Purity: | ≥98% |
Potent prostacyclin (PGI2) analog
| Chemical Name: | 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]acetic acid |
| Purity: | ≥98% |
