Catalog Number: 2833
Chemical Name: 3β-Hydroxy-1αH,5αH-tropane-2β-carboxylic acid methyl ester benzoate hydrochloride
Biological Activity
Competitive inhibitor of monoamine neurotransmitter transporters. Inhibits dopamine (DAT), serotonin (SERT) and noradrenalin (NET) transporters with Ki values are 267, 392 and 872 nM respectively. Psychostimulant.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity.
    Fleckenstein et al.
    Eur.J.Pharmacol., 2000;406:1
  2. Plasma membrane monoamine transporters: structure, regulation and function.
    Torres et al.
    Nat.Rev.Neurosci., 2003;4:13

The citations listed below are publications that use Tocris products. Selected citations for Cocaine hydrochloride include:

Showing Results 1 - 1 of 1

  1. A novel mechanism of cocaine to enhance dopamine d2-like receptor mediated neurochemical and behavioral effects. An in vivo and in vitro study.
    Authors: Ferraro Et al.
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