Cocaine hydrochloride

  ( 3 citations )    
Product Datasheet
Catalog Number:2833
Chemical Name:3β-Hydroxy-1αH,5αH-tropane-2β-carboxylic acid methyl ester benzoate hydrochloride
Product Details
Citations (3)
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Biological Activity
Competitive inhibitor of monoamine neurotransmitter transporters. Inhibits dopamine (DAT), serotonin (SERT) and noradrenalin (NET) transporters with Ki values are 267, 392 and 872 nM respectively. Psychostimulant.
Technical Data
  • M.Wt:
    339.81
  • Formula:
    C17H21NO4.HCl
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    53-21-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Cocaine hydrochloride include:

3 Citations: Showing 1 - 3
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  1. σ1 receptor ligands control a switch between passive and active threat responses.
    Authors: Rennekamp Et al.
    Nat Chem Biol  2016;12:552
  2. A novel mechanism of cocaine to enhance dopamine d2-like receptor mediated neurochemical and behavioral effects. An in vivo and in vitro study.
    Authors: Ferraro Et al.
    Neuropsychopharmacology  2012;37:1856
  3. Spike timing-dependent long-term potentiation in ventral tegmental area dopamine cells requires PKC.
    Authors: Luu and Malenka
    J Neurophysiol  2008;100:533

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