CP 339818 hydrochloride

Tocris Bioscience | Catalog # 1399

Non-peptide, potent KV1.3 channel blocker
Tocris Bioscience
Discontinued Product
1399 has been discontinued. View all Voltage-gated Potassium Channel Blockers products.

Key Product Details

Description

Non-peptide, potent KV1.3 channel blocker
View all Voltage-gated Potassium Channel Blockers »

Product Description

CP 339818 hydrochloride is a potent, non-peptide KV1.3 channel antagonist that preferentially binds to the C-type inactivated state of the channel (IC50 ~ 200 nM). Inhibits KV1.4 with an IC50 of ~ 300 nM. Selective over KV1.1, KV1.2, KV1.5, KV1.6, KV3.1-4, and KV4.2.

Product Specifications for CP 339818 hydrochloride

Molecular Weight

340.89

Formula

C21H24N2.HCl

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

N-[1-(Phenylmethyl)-4(1H)-quinolinylidene]-1 pentanamine hydrochloride

CAS Number

478341-55-8

PubChem ID

20761468

InChI Key

JIRISCAPZWLWCG-UHFFFAOYSA-N

SMILES

CCCCC\N=C2C1=CC=CC=C1N(CC3=CC=CC=C3)C=C/2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 20

Preparing Stock Solutions for CP 339818 hydrochloride

The following data is based on the product molecular weight 340.89.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 14.67 mL 73.34 mL 146.67 mL
1 mM 2.93 mL 14.67 mL 29.33 mL
2 mM 1.47 mL 7.33 mL 14.67 mL
10 mM 0.29 mL 1.47 mL 2.93 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 13 publications citing the usage of this product.

Product Documents for CP 339818 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CP 339818 hydrochloride

For research use only

Citations for CP 339818 hydrochloride

Customer Reviews for CP 339818 hydrochloride (1)

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  • CP 339818 hydrochloride was used to understand the blocking action on Kv7.1
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 01/23/2019
    The product was used to understand the blocking action on Kv7.1 on increasing concentrations.Its action on repolarization was being assessed.
    CP 339818 hydrochloride 1399

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