Catalog Number: 5495
Chemical Name: 4-Fluoro-N-[5-fluoro-6-(5-methoxypyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]benzamide
Biological Activity
cAMP/PKA/CREB pathway activator. Promotes osteogenic differentiation of human bone marrow-derived MSCs in vitro. Increases bone mass and bone volume density in ovariectomized mice.
Technical Data
  • M.Wt:
    420.37
  • Formula:
    C21H14F2N6O2
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    1134613-19-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. An activator of the cAMP/PKA/CREB pathway promotes osteogenesis from human mesenchymal stem cells.
    Kim et al.
    J.Cell.Physiol., 2013;228:617

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