D-erythro-Sphingosine (synthetic)

Key Product Details

Product Description

D-erythro-Sphingosine (synthetic) is an inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C.

Product Specifications for D-erythro-Sphingosine (synthetic)

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for D-erythro-Sphingosine (synthetic)

The following data is based on the product molecular weight 299.50.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

4 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	6.68 mL	33.39 mL	66.78 mL
2.5 mM	1.34 mL	6.68 mL	13.36 mL
5 mM	0.67 mL	3.34 mL	6.68 mL
25 mM	0.13 mL	0.67 mL	1.34 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Merrill Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds. Biochemistry 1989 PMID: 2742830
• Grossman Sphingosine inhibition and promotion of histamine release from isolated rat mast cells. Agents Actions 1990 PMID: 1707581

Product Documents for D-erythro-Sphingosine (synthetic)