(D)-PPA 1

   
Product Datasheet
Catalog Number:6515
Chemical Name:
Product Details
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Biological Activity
PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.
Technical Data
  • M.Wt:
    1555.67
  • Formula:
    C70H98N20O21
  • Sequence:
    NYSKPTDRQYHF

    (Modifications: Asn-1 = D-Asn, Tyr-2 = D-Tyr, Ser-3 = D-Ser, Lys-4 = D-Lys, Pro-5 = D-Pro, Thr-6 = D-Thr, Asp-7 = D-Asp, Arg-8 = D-Arg, Gln-9 = D-Gln, Tyr-10 = D-Tyr, His-11 = D-His, Phe-12 = D-Phe)

  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    1620813-53-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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VersaClone cDNA Plasmids
Description Application Cat# Citations Images  

Human PD-1 (NP_005009) VersaClone cDNA

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Cynomolgus Monkey PD-1 (NP_001271065) VersaClone cDNA

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Mouse PD-1 (NP_032824) VersaClone cDNA

RDC0893
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Canine PD-1 (NP_001301026) VersaClone cDNA

RDC2098
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