Catalog Number: 1417
Chemical Name: 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Biological Activity
Analog of the phytoestrogen genistein (Cat. No. 1110). Blocks G1 phase cell cycle progression. Agonist at estrogen receptors.
Technical Data
  • M.Wt:
    254.24
  • Formula:
    C15H10O4
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Desiccate at -20°C
  • CAS No:
    486-66-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Development effects of dietary phytoestrogens in Sprague Dawley rats and interactions of genistein and daidzein with rat estrogen receptors α and β in vitro.
    Casanova et al.
    Toxicol.Sci., 1999;51:236
  2. Daidzein inhibits insulin- or insulin-like growth factor-1-mediated signaling in cell cycle progression of Swiss 3T3 cells.
    Higashi and Ogawara
    Biochim.Biophys.Acta, 1994;1221:29
  3. Differentiation of promyelocytic leukemia cells HL-60 induced by daidzein in vitro and in vivo.
    Jing et al.
    Anticancer Res., 1993;13:1049

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