DDX18 Antibody

Novus Biologicals | Catalog # NB100-1722

Novus Biologicals
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all DDX18 Primary Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 625 and the C-terminus (residue 670) of human DEAD (Asp-Glu-Ala-Asp) Box Protein 18 using the numbering given in entry NP_006764.3 (GeneID 8886).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DDX18 Antibody

Western Blot: DDX18 Antibody [NB100-1722]

Western Blot: DDX18 Antibody [NB100-1722]

Western Blot: DDX18 Antibody [NB100-1722] - Detection of Human DDX18 on HeLa whole cell lysate using NB100-1722. DDX18 was also immunoprecipitated using rabbit anti-DDX18 antibody NB100-1721.

Applications for DDX18 Antibody

Application
Recommended Usage

Immunoprecipitation

1-4 ug/mg of lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: DDX18

DDX18 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX18 has been observed to be a target of myc-max heterodimers. Alternate names for DDX18 include ATP-dependent RNA helicase DDX18, DEAD box protein 18, myc-regulated DEAD box protein, and MrDb.

Alternate Names

DEAD (Asp-Glu-Ala-Asp) box polypeptide 18, DEAD box protein 18, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 18 (Myc-regulated), EC 3.6.1, EC 3.6.4.13, FLJ33908, MrDbATP-dependent RNA helicase DDX18, Myc-regulated DEAD box protein

Entrez Gene IDs

8886 (Human)

Gene Symbol

DDX18

UniProt

NP_006764.3 (Human)

Additional DDX18 Products

Product Documents for DDX18 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for DDX18 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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