Deguelin

Catalog # Availability Size / Price Qty
1770/10
Deguelin | CAS No. 522-17-8 | Apoptosis Inducer Compounds
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Description: Anticancer and antiviral agent; chemopreventive and pro-apoptotic

Chemical Name: (7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one

Purity: ≥97%

Product Details
Citations (2)
Reviews

Biological Activity

Anticancer and antiviral agent; chemopreventive and pro-apoptotic. Inhibits phorbol ester-induced ornithine decarboxylase and NADH:ubiquinone oxidoreductase activities (IC50 values are 11 and 6.9 nM respectively). Inhibits PI 3-kinase and reduces pAkt levels in pre-malignant and malignant human bronchial epithelial cells. Active in vivo.

Technical Data

M.Wt:
394.42
Formula:
C23H22O6
Solubility:
Soluble to 50 mM in ethanol and to 100 mM in DMSO
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
522-17-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Deguelin

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