Apoptosis Inducer Compounds: Products

"Apoptosis Inducer Compounds" has 44 results in Products.
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Doxorubicin hydrochloride

Antitumor antibiotic agent. Inhibits DNA topoisomerase II

Mitomycin C

DNA cross-linking antitumor agent

Cisplatin

Potent pro-apoptotic anticancer agent; activates caspase-3

Actinomycin D

Inhibits RNA polymerase

Oxaliplatin

DNA cross-linking antitumor agent

Cyclophosphamide

Alkylating agent; chemotherapeutic

Temozolomide

DNA-methylating antitumor agent

Streptozocin

DNA alkylator; antitumor and induces diabetes

Carboplatin

DNA cross-linking antitumor agent

Curcumin

Antitumor, anti-inflammatory and antioxidant

Triptolide

Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive

Fludarabine

Purine analog; inhibits DNA synthesis

iMDK

Suppressor of MDK expression; inhibits PI 3-K signaling

Embelin

Inhibitor of X-linked inhibitor of apoptosis (XIAP); cell-permeable and antitumor

C 75

Potent fatty acid synthase inhibitor; proapoptotic

Kaempferol

Proapoptotic; downregulates PLK1 expression and activates mitochondrial Ca2+ uniporter

CHM 1

Potent antitumor agent; inducer of apoptosis

FK 866 hydrochloride

Non-competitive and potent NAMPT inhibitor; induces apoptosis and autophagy

SMBA 1

High affinity and selective activator of Bax

Deguelin

Anticancer and antiviral agent; chemopreventive and pro-apoptotic

2-Methoxyestradiol

Apoptotic and antiangiogenic agent

Apoptosis Activator 2

Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis

2,3-DCPE hydrochloride

Selectively induces cancer cell apoptosis

AT 101

Downregulates Bcl-2 and Mcl-1; pro-apoptotic

Oncrasin 1

Induces abnormal nuclear aggregation of PKCι; proapoptotic

Gambogic acid

Apoptosis inducer. Activates caspases and inhibits Bcl-2 family proteins

Bendamustine hydrochloride

Cytostatic agent; exhibits DNA alkylating and purine analog properties

Narciclasine

Stimulates RhoA activation; antiproliferative agent that slows cell cycle progression

Betulinic acid

Antitumor and anti-HIV agent; activates NF-κB. Also TGR5 agonist

Piperlongumine

Induces apoptosis; increases p53 and ROS levels in cancer cells

NSC 687852

Inhibitor of UCHL5 and USP14

PCI 34051

Potent and selective HDAC8 inhibitor

Plumbagin

Induces G2/M cell cycle arrest; anticancer

BAM 7

Selective Bax activator; induces Bax-mediated apoptosis

Apicidin

Potent histone deacetylase inhibitor

CFM 4

CARP-1 mimetic; proapoptotic

UC 112

IAP and XIAP inhibitor; antitumor

Cladribine

Deoxyadenosine analog; pro-apoptotic

CHMFL-FLT3-122

Potent and selective FLT3 inhibitor

TW 37

Bcl-2 inhibitor; induces apoptosis

Bioymifi

DR5 (TRAIL receptor) agonist; induces apoptosis

MRT 68921 dihydrochloride

Potent ULK inhibitor; inhibits autophagy

Chaetoglobosin A

Antibiotic; selectively induces apoptosis of CLL cells

Oleanolic acid

Selective GPBA receptor (TGR5) partial agonist
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