DHBP dibromide
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Description: Ca2+ release inhibitor
Chemical Name: 1,1'-Diheptyl-4,4'-bipyridinium dibromide
Biological Activity
Blocks calcium release from sarcoplasmic reticulum by direct interaction with the ryanodine receptor.Technical Data
M.Wt:
514.39
Formula:
C24H38Br2N2
Solubility:
Soluble to 100 mM in water
Storage:
Store at RT
CAS No:
6159-05-3
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Effects of bipyridylium compounds on calcium release from triadic vesicles isolated from rabbit skeletal muscle.
Kang et al.
Br.J.Pharmacol., 1994;112:1216
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