Diazoxide

  ( 3 citations )    
Product Datasheet
Catalog Number:0964
Chemical Name:7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
Product Details
Citations (3)
Reviews
Biological Activity
Antihypertensive, activates ATP-dependent K+ channels (Kir6). Induces activation of PKCε, an intermediate in the opening of mitoKATP channels, results in cardioprotection against hypoxia-induced death. Blocks desensitization of AMPA receptors.
Technical Data
  • M.Wt:
    230.67
  • Formula:
    C8H7ClN2O2S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    364-98-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Diazoxide include:

3 Citations: Showing 1 - 3
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  1. Label-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel.
    Authors: Sun Et al.
    Sci Rep  2014;4:4934
  2. Chronic neonatal diazoxide therapy is not associated with adverse effects
    Authors: Cox Et al.
    J Neurosci  2014;14:49
  3. Sex differences in the contribution of ATP-sensitive K+ channels in trigeminal ganglia under an acute muscle pain condition.
    Authors: Niu Et al.
    Neuroscience  2011;180:344

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