Diprenorphine

Tocris Bioscience | Catalog # 2965

Non-selective opioid antagonist
Tocris Bioscience
Discontinued Product
2965 has been discontinued. View all Miscellaneous/Non-selective Opioid Antagonists products.

Key Product Details

Description

Non-selective opioid antagonist
View all Miscellaneous/Non-selective Opioid Antagonists »

Product Description

Diprenorphine is a non-selective opioid receptor antagonist (Ki values are 0.017, 0.072 and 0.23 nM for κ-, μ- and δ-opioid receptors).

Product Specifications for Diprenorphine

Molecular Weight

425.56

Formula

C26H35NO4

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

17-(Cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-6,14-ethenomorphinan-7-methanol

CAS Number

14357-78-9

PubChem ID

443408

InChI Key

OIJXLIIMXHRJJH-KNLIIKEYSA-N

SMILES

OC1=CC=C3C2=C1O[C@@H]([C@]7(OC)[C@@H]([C@@](C)(O)C)C4)[C@]52[C@@]4(CC7)[C@H](N(CC6CC6)CC5)C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 8.51 20
Ethanol 10.64 25

Preparing Stock Solutions for Diprenorphine

The following data is based on the product molecular weight 425.56.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 9.40 mL 47.00 mL 93.99 mL
1.25 mM 1.88 mL 9.40 mL 18.80 mL
2.5 mM 0.94 mL 4.70 mL 9.40 mL
12.5 mM 0.19 mL 0.94 mL 1.88 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 45 publications citing the usage of this product.

Product Documents for Diprenorphine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Diprenorphine

For research use only

Customer Reviews for Diprenorphine (1)

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  • Diprenorphine in binding experiment
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 01/13/2020
    Diprenorphine was use to displace radiolabeled-diprenorphine in an homologous radiobinding assay.
    Diprenorphine 2965

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