(±)-Vesamicol hydrochloride

Key Product Details

Product Description

(±)-Vesamicol hydrochloride is an inhibitor of acetylcholine transport (K_i = 2 nM). Centrally active following systemic administration in vivo.

Product Specifications for (±)-Vesamicol hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for (±)-Vesamicol hydrochloride

The following data is based on the product molecular weight 295.85.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	6.76 mL	33.80 mL	67.60 mL
2.5 mM	1.35 mL	6.76 mL	13.52 mL
5 mM	0.68 mL	3.38 mL	6.76 mL
25 mM	0.14 mL	0.68 mL	1.35 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Kobayashi Effects of systemic administration of 2-(4-phenyl-piperidino)-cyclohexanol (vesamicol) and an organophosphate DDVP on the cholinergic system in brain regions of rats. Brain Res.Bull. 1997 PMID: 9205789
• Varoqui and Erickson Active transport of acetylcholine by the human vesicular acetylcholine transporter. J.Biol.Chem. 1996 PMID: 8910293
• Efange N-hydroxyalkyl derivatives of 3β-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters. J.Med.Chem. 1997 PMID: 9397171

Product Documents for (±)-Vesamicol hydrochloride