Eg5 Antibody

Name: Eg5 Antibody
Brand: Novus Biologicals
SKU: NB100-57514
Price: 459 USD
Availability: InStock

Novus Biologicals | Catalog # NB100-57514

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Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

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Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1006 and the C-terminus (residue 1056) of human kinesin-related motor protein Eg5 (kinesin family member 11) using the numbering given in entry NP_004514.2 (GeneID 3832).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Eg5 Antibody

Western Blot: Eg5 Antibody [NB100-57514]

Western Blot: Eg5 Antibody [NB100-57514] - Detection of Human EG5/KIF11 on HeLa whole cell lysate using NB100-57514. EG5/KIF11 was also immunoprecipitated by rabbit anti-EG5/KIF11 antibody NB100-57513.

Applications for Eg5 Antibody

Application

Recommended Usage

Immunoprecipitation

2 - 5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Eg5

The kinesin superfamily of proteins consists of forty five KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. EG5/KIF11 plays a role in spindle-pole formation and chromosome positioning and separation. Alternate names for EG5/KIF11 include kinesin-like protein KIF11, kinesin-related motor protein Eg5, kinesin-like spindle protein HKSP, thyroid receptor-interacting protein 5, TRIP-5, kinesin-like protein 1, and KNSL1.

Long Name

Kinesin-like protein KIF11

Alternate Names

KIF11, KNSL1, TRIP-5, TRIP5

Entrez Gene IDs

3832 (Human)

Gene Symbol

KIF11

UniProt

NP_004514.2 (Human)

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Product Documents for Eg5 Antibody

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Certificate of Analysis

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Product Specific Notices for Eg5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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