Antibiotic antitumor agent. Inhibits the synthesis and function of DNA (IC50
= 62.7 μ
M in rat glioblastoma cell lines) and inhibits the relaxing property of topoisomerase II.
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All Tocris products are intended for laboratory research use only.
Epirubicin: a review of pharmacology, clinical activity, and adverse effects of an adriamycin analogue.
Cersosimo et al.
DNA polymerases and DNA topoisomerases as targets for the development of anticancer drugs.
Spadari et al.
Anticancer Res., 1986;6:935
Comparative activity of anthracycline 13-dihydrometabolites against rat glioblastoma cells in culture.
Schott and Robert
The citations listed below are publications that use Tocris products. Selected citations for Epirubicin hydrochloride include:
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