Home / DNA, RNA and Protein Synthesis Inhibitors / Epirubicin hydrochloride

Epirubicin hydrochloride

Catalog #: 3260
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3260/10
Epirubicin hydrochloride | CAS No. 56390-09-1 | DNA, RNA and Protein Synthesis Inhibitors
1 Image
Description: Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II
Alternative Names: 4'-Epidoxorubicin

Chemical Name: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride

Purity: ≥96%

Product Details
Citations (2)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Epirubicin hydrochloride is an antibiotic antitumor agent. Inhibits the synthesis and function of DNA (IC50 = 62.7 μM in rat glioblastoma cell lines) and inhibits the relaxing property of topoisomerase II.

Technical Data

M.Wt:
579.98
Formula:
C27H29NO11.HCl
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in water
Purity:
≥96%
Storage:
Desiccate at +4°C
CAS No:
56390-09-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

COA view current batch
Or select another batch:
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Epirubicin hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Epirubicin hydrochloride include:

2 Citations: Showing 1 - 2

  1. A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier.
    Authors: Kim and Bynoe
    J Clin Invest  2016;126:1717
  2. RB1 status in triple negative breast cancer cells dictates response to radiation treatment and selective therapeutic drugs.
    Authors: Robinson Et al.
    PLoS One  2013;8:e78641

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Epirubicin hydrochloride

There are currently no reviews for this product. Be the first to review Epirubicin hydrochloride and earn rewards!

Have you used Epirubicin hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.