Epirubicin hydrochloride

Catalog # Availability Size / Price Qty
3260/10
Epirubicin hydrochloride | CAS No. 56390-09-1 | DNA, RNA and Protein Synthesis Inhibitors
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Description: Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II
Alternative Names: 4'-Epidoxorubicin

Chemical Name: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride

Purity: ≥96%

Product Details
Citations (2)
Reviews (1)

Biological Activity

Antibiotic antitumor agent. Inhibits the synthesis and function of DNA (IC50 = 62.7 μM in rat glioblastoma cell lines) and inhibits the relaxing property of topoisomerase II.

Technical Data

M.Wt:
579.98
Formula:
C27H29NO11.HCl
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in water
Purity:
≥96%
Storage:
Desiccate at +4°C
CAS No:
56390-09-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Epirubicin hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Epirubicin hydrochloride include:

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Epirubicin effectively kills melanoma cells in vitro
By Anonymous on 02/14/2019
Species: Human

Epirubicin was used at a 20 uM concentration for in vitro culture with SK-MEL-28 and cell viability was monitored over time with live imaging. Arrow indicates when compound was added to media.


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