Epirubicin hydrochloride

  ( 2 citations )    
Product Datasheet
Catalog Number:3260
Alternate Names:4'-Epidoxorubicin
Chemical Name:(8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride
Product Details
Citations (2)
Reviews
Biological Activity
Antibiotic antitumor agent. Inhibits the synthesis and function of DNA (IC50 = 62.7 μM in rat glioblastoma cell lines) and inhibits the relaxing property of topoisomerase II.
Technical Data
  • M.Wt:
    579.98
  • Formula:
    C27H29NO11.HCl
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in ethanol
  • Purity:
    >97
  • Storage:
    Desiccate at +4°C
  • CAS No:
    56390-09-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Epirubicin hydrochloride include:

2 Citations: Showing 1 - 2
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  1. A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier.
    Authors: Kim and Bynoe
    J Clin Invest  2016;126:1717
  2. RB1 status in triple negative breast cancer cells dictates response to radiation treatment and selective therapeutic drugs.
    Authors: Robinson Et al.
    PLoS One  2013;8:e78641

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