DNA, RNA and Protein Synthesis Inhibitors: Products

mRNA splicing inhibitor; antitumor

JNK, SAPK and p38 activator

DNA cross-linking antitumor agent

Inhibitor of protein synthesis

DNA cross-linking antitumor agent

Thymidylate synthetase inhibitor

Nucleoside analog; inhibits DNA replication

Inhibits RNA polymerase

Protein synthesis inhibitor

DNA cross-linking antitumor agent

Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive

DNA synthesis inhibitor

Topoisomerase II inhibitor

Aminoglycoside antibiotic; used in cell culture

Thymidylate synthetase inhibitor

RNA synthesis inhibitor

Inhibits viral DNA polymerase; antiherpetic agent

Purine analog; inhibits DNA synthesis

Antibiotic; inhibits bacterial DNA synthesis

Inhibitor of RNA polymerase II

Pregnane X receptor agonist; antibiotic

Cytotoxic nucleoside analog; inhibits RNA synthesis

PCNA inhibitor

Inhibits eIF4E:eIF4G subunit interaction

Werner syndrome helicase (WRN) inhibitor

DNA polymerase α, δ and ε inhibitor

RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor

Pre-mRNA splicing inhibitor; cell permeable

Cx36 and Cx50 gap channel blocker; also antimalarial and antischistosomal

Inhibitor of protein synthesis; antileukemic agent

DNA topoisomerase II inhibitor

Inhibitor of DNA and RNA polymerase

Inhibitor of human telomerase activity

Selective telomerase inhibitor

Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II

Antibiotic; inhibits protein synthesis in gram-positive bacteria

Antibiotic; inhibits bacterial DNA synthesis

Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria

Inhibitor of RNA helicase A (RHA)

Purine analog; inhibits DNA and RNA synthesis

Blocks eIF4E activity; antiviral guanosine analog

Prodrug of 5-Fluorouracil (Cat. No. 3257). Inhibits DNA synthesis

RNA polymerase I inhibitor; also p53 pathway activator

Allosteric inhibitor of RAD52; also APE1 inhibitor

High affinity competitive prolyl-tRNA synthetase inhibitor

Telomerase inhibitor

Purine nuceloside analog; inhibits DNA synthesis

RAD51 recombinase inhibitor

Inhibits formation of miR-210

Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation