40 results for "DNA, RNA and Protein Synthesis Inhibitors" in Products
DNA, RNA and Protein Synthesis Inhibitors
RNA, DNA and protein synthesis are fundamental processes necessary for all life.
RNA synthesis (transcription) begins by uncoiling a section of DNA that will be used as the template. RNA polymerase binds to a promoter sequence and initiates separation of the DNA double helix. Complementary ribonucleotides align and RNA polymerase catalyzes their polymerization. The newly synthesized RNA strand undergoes post-transcriptional processing before it leaves the nucleus.
Protein synthesis ...
DNA cross-linking antitumor agent
| Alternate Names: | Ametycine |
| Chemical Name: | [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione |
| Purity: | ≥98% |
JNK, SAPK and p38 activator
| Chemical Name: | (2R,3S,4S)-2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate |
| Purity: | ≥98% |
Protein synthesis inhibitor
| Chemical Name: | 3'-[α-Amino-p-methoxyhydrocinnamamido]-3'-deoxy-N,N-dimethyladenosine dihydrochloride |
| Purity: | ≥98% |
mRNA splicing inhibitor; antitumor
| Chemical Name: | (4R,7R,8S,9E,11S,12S)-8-(Acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyloxacyclododec-9-en-2-one |
| Purity: | ≥95% |
Inhibitor of protein synthesis
| Chemical Name: | 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione |
| Purity: | ≥97% |
Inhibits RNA polymerase
| Chemical Name: | 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide |
| Purity: | ≥95% |
Thymidylate synthetase inhibitor
| Alternate Names: | 5-FU |
| Chemical Name: | 5-Fluoro-2,4-(1H,3H)-pyrimidinedione |
| Purity: | ≥98% |
DNA cross-linking antitumor agent
| Alternate Names: | Eloxatin |
| Chemical Name: | Oxalato[(1R-trans)-1,2-cyclohexanediamine]platinum(II) |
| Purity: | ≥98% |
Inhibitor of DNA and RNA polymerase
| Chemical Name: | (1S)-5-Deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1.fwdarw.3)-O-2,6-dideoxy-β-D-lyxo-hexopyranosyl-(1.fwdarw.3)-2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose |
| Purity: | ≥95% |
DNA cross-linking antitumor agent
| Alternate Names: | NSC 241240,Paraplatin,JM 8 |
| Chemical Name: | cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) |
| Purity: | ≥98% |
Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
| Chemical Name: | (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one |
| Purity: | ≥98% |
DNA synthesis inhibitor
| Chemical Name: | (+)-2'-Deoxy-2',2'-difluorocytidine hydrochloride |
| Purity: | ≥98% |
Purine analog; inhibits DNA synthesis
| Chemical Name: | 9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine |
| Purity: | ≥98% |
Nucleoside analog; inhibits DNA replication
| Alternate Names: | Cytosine b-D-arabinofuranoside |
| Chemical Name: | 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone |
| Purity: | ≥98% |
DNA topoisomerase II inhibitor
| Alternate Names: | Daunomycin |
| Chemical Name: | (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyransoyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride |
| Purity: | ≥98% |
Inhibitor of protein synthesis; antileukemic agent
| Chemical Name: | Cephalotaxine 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate |
| Purity: | ≥98% |
RNA synthesis inhibitor
| Chemical Name: | 3'-Deoxyadenosine |
| Purity: | ≥98% |
Selective telomerase inhibitor
| Chemical Name: | 2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl1-yl]amino]benzoic acid |
| Purity: | ≥98% |
Antibiotic; inhibits bacterial DNA synthesis
| Chemical Name: | (S)-3,6-Diamino-N-((3S,9S,12S,15S,Z)3((2R,4S)-6-amino-4-hydroxy-1,2,3,4-tetrahydropyridin-2-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-15-yl)hexanamide disulfate |
Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria
| Alternate Names: | LY 146032 |
| Chemical Name: | N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-benzene butanoic acid (13-4) lactone |
| Purity: | ≥95% |
Inhibits eIF4E:eIF4G subunit interaction
| Chemical Name: | α-[2-[4-(3,4-Dichlorophenyl)-2-thiazolyl]hydrazinylidene]-2-nitro-benzenepropanoic acid |
| Purity: | ≥98% |
DNA polymerase α, δ and ε inhibitor
| Chemical Name: | (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol |
| Purity: | ≥98% |
Cx36 and Cx50 gap channel blocker; also antimalarial and antischistosomal
| Chemical Name: | (αS)-rel-α-(2R)-2-Piperidinyl-2,3-bis(trifluoromethyl-4-quinolinemethanol hydrochloride |
| Purity: | ≥98% |
Topoisomerase II inhibitor
| Alternate Names: | ICRF-187 |
| Chemical Name: | 4-[(2S)-2-(3,5-Dioxopiperazin-1-yl)propyl]piperazine-2,6-dione hydrochloride |
| Purity: | ≥98% |
Antibiotic; inhibits bacterial DNA synthesis
| Alternate Names: | CP 99219 |
| Chemical Name: | 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid mesylate |
| Purity: | ≥98% |
