Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 311007
View all Exostosin-like 3/EXTL3 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Exostosin-like 3/EXTL3
Thr52-Ile919
Accession # O43909

Specificity

Detects human Exostosin-like 3/EXTL3 in direct ELISAs and Western blots.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Exostosin-like 3/EXTL3 Antibody (311007) [FITC]

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Exostosin-like 3/EXTL3

EXTL3, also referred to as Exostosin-like 3, is a glycosyltransferase and a critical player in the control of keratinocyte proliferation and differentiation via its interaction with REG3A. EXTL3 is 919 amino acids in length and approximately 105kDa. Current research surrounding EXTL3 has shown a possible link with several diseases and disorders such as colorectal cancer, HIV, hepatitis, gonorrhea, syphilis, exostosis, pancreatitis and rheumatic aortic stenosis. EXTL3 has also been shown to interact with Fyn, Crk, Phospholipase C gamma 1, PI 3 Kinase p85 alpha, and PEPP2 in pathways such as Glycosaminoglycan biosynthesis, heparan sulfate biosynthesis, the activation of Chaperones by IRE1alpha, and protein metabolism pathways.

Alternate Names

Exostosin like 3, EXTL3

Gene Symbol

EXTL3

Additional Exostosin-like 3/EXTL3 Products

Product Documents for Exostosin-like 3/EXTL3 Antibody (311007) [FITC]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Exostosin-like 3/EXTL3 Antibody (311007) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Glycobiology-related Enzymes

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