Human Exostosin-like 3/EXTL3 Antibody

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Human Exostosin-like 3/EXTL3 Antibody Summary

Species Reactivity
Detects human Exostosin-like 3/EXTL3 in direct ELISAs and Western blots.
Monoclonal Mouse IgG2A Clone # 311007
Protein A or G purified from hybridoma culture supernatant
Mouse myeloma cell line NS0-derived recombinant human Exostosin-like 3/EXTL3
Accession # O43909
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
1 µg/mL
Recombinant Human Exostosin-like 3/EXTL3
25 µg/mL
Conditioned cell culture medium spiked with Recombinant Human Exostosin-like 3/EXTL3, see our available Western blot detection antibodies

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Exostosin-like 3/EXTL3

EXTL3 is an ER-resident type II transmembrane protein belonging to the EXT family of tumor suppressor genes. EXT family members are glycosyl transferases that are involved in the synthesis of the glycosaminoglycan chains of heparan sulfate proteoglycans. EXTL3 was also reported to be a receptor for the REG protein, a pancreatic beta-cell regeneration factor. The amino acid sequence of rhEXTL3 is 98%, 97%, 88%, and 83% identical to that of dog, rat/mouse, Xenopus and zebrafish.

Entrez Gene IDs
2137 (Human)
Alternate Names
botv; DKFZp686C2342; EC; exostoses (multiple)-like 3; Exostosin like 3; Exostosin-like 3; EXTL1L; EXTL3; EXTR1BOTV; EXT-related protein 1; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Hereditary multiple exostoses gene isolog; KIAA0519; Multiple exostosis-like protein 3; Putative tumor suppressor protein EXTL3; reg receptor; REG; REGR; RPR

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