FANCL Antibody

Novus Biologicals | Catalog # NBP1-49839

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all FANCL Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-QNLKDVLEIDFP corresponding to internal region according to NP_060532.2.

Epitope

QNLKDVLEIDFP - internal region

Specificity

This antibody is expected to recognize both isoforms (NP_001108108.1; NP_060532.2).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for FANCL Antibody

Western Blot: FANCL Antibody [NBP1-49839]

Western Blot: FANCL Antibody [NBP1-49839]

Western Blot: FANCL Antibody [NBP1-49839] - Analysis of FANCL in Human Bone Marrow lysate (35ug protein in RIPA buffer) NBP1-49839 at 1 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for FANCL Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 45 kDa band observed in human bone marrow lysates (calculated MW of 43.4 kDa band according to NP_001108108.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FANCL

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]

Alternate Names

E3 ubiquitin-protein ligase FANCL, EC 6.3.2.-, FAAP43PHF9FLJ10335, Fanconi anemia group L protein, Fanconi anemia, complementation group L, Fanconi anemia-associated polypeptide of 43 kDa, PHD finger protein 9, POG

Entrez Gene IDs

55120 (Human); 67030 (Mouse); 305600 (Rat)

Gene Symbol

FANCL

UniProt

NP_001108108.1 (Human)

Additional FANCL Products

Product Documents for FANCL Antibody

Certificate of Analysis

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Product Specific Notices for FANCL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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