Fc gamma RIIA/CD32a Antibody Pair [HRP]

Novus Biologicals | Catalog # NBP2-79663

Novus Biologicals
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Key Product Details

Assay Type

Sandwich ELISA

Assay Range

7.81-500 pg/ml (example only; lot dependent)

Sensitivity

7.8 pg/ml (example only; lot dependent)

Reactivity

Rhesus Macaque
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Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Rhesus Macaque Fc gamma RIIA/CD32a.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for Fc gamma RIIA/CD32a Antibody Pair [HRP]

Sandwich ELISA: Fc gamma RIIA/CD32a Antibody Pair [HRP] [NBP2-79663] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for Fc gamma RIIA/CD32a Antibody Pair [HRP]

  • Mouse Monoclonal Capture Antibody
  • Mouse Monoclonal Detection Antibody (HRP-conjugated)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Fc gamma RIIA/CD32a

The FCGR2A gene encodes a low affinity immunoglobulin gamma Fc region receptor II-a protein that in isoform 1 is 317 amino acids long at 35 kDA and at isoform 2 is 316 amino acids long at nearly 35 kDA. These proteins are found on the surface of many immune system response cells that act as a low affinity receptor through encouraging responses against pathogens and soluble antigens. Additionally, it functions to initiate phagocytosis of opsonized antigens. FCGR2A participates in Fc-GammaR pathway, osteoclast differentiation, signaling events controlled by PTP1B, and NFAT in immune response. It is known to interact with genes SYK, FYN, HCK, LGALS3, and PIK3R1. FCGR2A is linked to lupus, thrombocytopenia, b-cell lymphomas, otitis media, adult-onset still's disease, guillain-barre syndrome, asymptomatic dengue, severe acute respiratory syndrome.

Long Name

Fc gamma Receptor II A

Alternate Names

CD32a, FCGR2A, FcgRIIA, FCRIIA

Gene Symbol

FCGR2A

Additional Fc gamma RIIA/CD32a Products

Product Documents for Fc gamma RIIA/CD32a Antibody Pair [HRP]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Fc gamma RIIA/CD32a Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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FAQs for Fc gamma RIIA/CD32a Antibody Pair [HRP]

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  • Q: Does any of your FCGR2A antibodies (19C10, 6D11, 13G9) cross react to FCGR2B?

    A: For these antibodies, we have used the full-length protein FCGR2A (NP_067674) as the immunogen and we have not mapped the epitope that is detected with each Ab yet. I did an alignment of these two proteins and they are highly conserved thus it seems likely that there will be cross-reactivity.

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