Biological Activity Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.
Soluble to 100 mM in DMSO
Store at RT
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For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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