FH 535

   
Product Datasheet
Catalog Number:4344
Chemical Name:2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide
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Biological Activity
Inhibitor of Wnt/β-catenin signaling and dual antagonist of PPARγ/δ activity. Suppresses β-catenin/Tcf-mediated transcription; inhibits β-catenin and GRIP1 recruitment to PPARγ and δ. Exhibits antiproliferative effects in transformed colon, lung and liver cancer cell lines.
Technical Data
  • M.Wt:
    361.2
  • Formula:
    C13H10Cl2N2O4S
  • Solubility:
    Soluble to 75 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    108409-83-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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