Furanone C-30

Catalog # Availability Size / Price Qty
6546/10
Cat.No. 6546 - Furanone C-30 | C5H2Br2O2 | CAS No. 247167-54-0
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Description: Quorum sensing inhibitor; antibacterial

Chemical Name: (5Z)-4-Bromo-5-(bromomethylene)-2(5H)-furanone

Purity: ≥98%

Product Details
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Biological Activity

Synthetic furanone bacterial quorum sensing inhibitor. Inhibits virulence factor expression in Pseudomonas aeruginosa and increases bacterial susceptibility to antibiotics in vitro. Also inhibits bacterial quorum sensing in vivo and promotes bacterial clearance in a mouse pulmonary infection model.

Technical Data

M.Wt:
253.88
Formula:
C5H2Br2O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
247167-54-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors.
    Hentzer et al.
    EMBO J., 2003;22:3803

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