FXYD5/Dysadherin Antibody (CL14037) - BSA Free

Novus Biologicals | Catalog # NBP3-24585

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL14037

Format

BSA Free
View all FXYD5/Dysadherin Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from Q96DB9, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for FXYD5/Dysadherin Antibody (CL14037) - BSA Free

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14037) [NBP3-24585]

Staining of human pancreas shows strong membranous positivity in exocrine glandular cells.

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14037) [NBP3-24585]

Staining of human breast cancer shows strong membranous positivity in tumor cells.

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14037) [NBP3-24585]

Staining of human ovarian cancer (papillary carcinoma) shows strong membranous positivity in tumor cells.

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14037) [NBP3-24585]

Staining of human tonsil shows moderate membranous positivity in lymphoid cells.

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14037) [NBP3-24585]

Staining of human fallopian tube shows moderate membranous and cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14037) [NBP3-24585]

Staining of human ovarian cancer (high grade serous carcinoma) shows strong membranous positivity in tumor cells.

Applications for FXYD5/Dysadherin Antibody (CL14037) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FXYD5/Dysadherin

Dysadherin encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane.

Long Name

FXYD Domain-containing Ion Transport Regulator 5

Alternate Names

DYSAD, Dysadherin, EF-8, IWU1, KCT1, OIT2, PRO6241, RIC

Gene Symbol

FXYD5

Additional FXYD5/Dysadherin Products

Product Documents for FXYD5/Dysadherin Antibody (CL14037) - BSA Free

Certificate of Analysis

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Product Specific Notices for FXYD5/Dysadherin Antibody (CL14037) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Biomarkers

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Protocols

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