Galangin

Catalog # Availability Size / Price Qty
6494/25
Cat.No. 6494 - Galangin | C15H10O5 | CAS No. 548-83-4
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Description: TRPC5 inhibitor; also induces autophagy

Chemical Name: 3,5,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one

Purity: ≥98%

Product Details
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Biological Activity

TRPC5 inhibitor. Inhibits Ca2+ entry into TRPC5 expressing cells. Inhibits LPS-induced expression of TNFα, IL-6, IL-1β, COX2 and iNOS, in vitro. Attenuates microglial activation, loss of dopaminergic neurons and motor dysfunction in a LPS-induced rat model of Parkinson's disease. Also inhibits proliferation in breast cancer cell lines. Induces autophagy.

Technical Data

M.Wt:
270.24
Formula:
C15H10O5
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
548-83-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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