GBR 13069 dihydrochloride
Chemical Name: (1-(2-(Bis-(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine dihydrochloride
Biological ActivityA potent inhibitor of dopamine uptake (IC50 = 40 nM). Centrally active following systemic administration in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Behavioural properties of GBR12909, GBR13069 and GBR13098: specific inhibitors of dopamine uptake.
Heikkila et al.
Prevention of the nigrostriatal toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by inhibitors of 3,4-dihydroxyphenylethylamine transport.
Mayer et al.
Interaction between substituted 1-[2-diphenylmethoxyethyl]piperazines and dopamine receptors.
Van der Zee and Hespe
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