Recombinant Human GNG11 His Protein

Novus Biologicals | Catalog # NBP2-51549

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
View all GNG11 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-70 of Human GNG11

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPALHIE DLPEKEKLKM EVEQLRKEVK LQRQQVSKCS EEIKNYIEER SGEDPLVKGI PEDKNPFKEK GSC

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

10.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human GNG11 His Protein

SDS-PAGE: Recombinant Human GNG11 His Protein [NBP2-51549]

SDS-PAGE: Recombinant Human GNG11 His Protein [NBP2-51549]

SDS-Page: GNG11 Recombinant Protein [NBP2-51549] - 15% SDS Page (3 ug)
SDS-PAGE: Recombinant Human GNG11 His Protein [NBP2-51549]

SDS-PAGE: Recombinant Human GNG11 His Protein [NBP2-51549]

SDS-Page: GNG11 Recombinant Protein [NBP2-51549] - 15% SDS Page (3 ug)

Formulation, Preparation, and Storage

NBP2-51549
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 10% glycerol, 1 mM DTT
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GNG11

GNG11, also known as Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11, is a 73 amino acid that is 8 kDa, plays a role in transmembrane signaling system, its beta and gamma chains are essential for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. This protein has been linked to splenic marginal zone lymphoma disease. The GNG11 protein has shown an interaction with ZHX1, GNB1, SMURF1, AMOTL2, GCG, and over 20 other proteins in several pathways including chemokine signaling pathway, glutamatergic synapse, cholinergic synapse, signal transduction cAMP signaling, G-protein signaling regulation of p38 and JNK signaling mediated by G-proteins, G-protein signaling G-Protein alpha-i signaling cascades, inhibitory action of lipoxins and resolvin E1 on neutrophil functions, signal transduction activation of PKC via G-Protein coupled receptor, molecular mechanisms of cancer, intracellular calcium signaling, CDK5 pathway, JNK pathway, and ERK5 signaling.

Alternate Names

GNGT11G protein gamma-11 subunit, guanine nucleotide binding protein (G protein), gamma 11, guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-11 subunit, guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11

Gene Symbol

GNG11

Additional GNG11 Products

Product Documents for Recombinant Human GNG11 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human GNG11 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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